Ronaldo, who scored a hat-trick against Atletico Madrid in the Champions League in midweek, was rested.
Genoa took full advantage, with substitute Stefano Sturaro scoring against his former club before Goran Pandev also found the net.
Juventus’ Paulo Dybala earlier had an effort ruled out for offside by VAR.
More to follow…
Stefano Sturaro scored the opener for Genoa against Juventus shortly after coming on
Sturaro stunned Juventus when he found the back of the net in the 72nd minute
Goran Pandev celebrates after he scored Genoa’s second goal against Juventus
Paulo Dybala thought he had put Juventus in front but the goal was ruled out by VAR
Genoa’s Cristian Kouame competes for the ball with Juventus defender Leonardo Bonucci
Genoa: Radu; Pedro Pereira, Romero, Zukanovic, Criscito; Lerager, Radovanovic (Miguel Veloso 75), Rolon, Lazovic (Sturaro 70); Sanabria (Pandev 60), Kouame
Subs not used: Lapadula, Mazzitelli, Gunter, Dalmonte, Bessa, Marchetti, Biraschi, Pezzella, Jandrei
Booked: Romero, Pandev
Goals: Sturaro 72, Pandev 81
Juventus: Perin; Caceres, Bonucci, Rugani; Pjanic; Joao Cancelo (Bernadeschi 60), Can, Bentancur (Spinazzola 77), Alex Sandro; Dybala, Mandzukic (Kean 73)
Subs not used: Nicolussi, Pinsoglio, Szczesny, Matuidi, Chiellini, Pablo Moreno
Booked: Caceres, Alex Sandro, Can
Juventus’ Emre Can looks to get the better of Genoa’s Pedro Pereira in the Serie A clash
Genoa midfielder Esteban Rolon battles for possession with Juventus star Paulo Dybala
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